FITC标记的整联蛋白重复蛋白3抗体
产品名称： FITC标记的整联蛋白重复蛋白3抗体
英文名称： Anti-ITFG3/FITC
产品编号： HZ-9633R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ITFG3/FITC Conjugated antibody
FITC标记的整联蛋白重复蛋白3抗体
| 产品编号 | bs-9633R-FITC |
| 英文名称 | Anti-ITFG3/FITC |
| 中文名称 | FITC标记的整联蛋白重复蛋白3抗体 |
| 别 名 | Protein ITFG3; Chromosome 16 open reading frame 9; gs19; integrin alpha FG-GAP repeat containing 3; ITFG3; ITFG3_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 细胞凋亡 细胞粘附分子 细胞分化 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 60kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ITFG3/C16orf9 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Integrins are heterodimers composed of noncovalently associated transmembrane Alpha and Beta subunits. The sixteen Alpha and eight Beta subunits heterodimerize to produce more than 20 different receptors. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. In addition to mediating cell adhesion and cytoskeletal organization, Integrins function as signaling receptors. Signals transduced by Integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. ITFG3 (Integrin alpha FG-GAP repeat containing 3), also known as C16orf9, is a 552 amino acid single-pass transmembrane protein that contains FG-GAP repeats, a motif commonly found in Integrin proteins. There are two isoforms of ITFG3 that are produced as a result of alternative splicing events. Subcellular Location: Membrane; Single-pass type II membrane protein (Potential). Similarity: Belongs to the ITFG3 family. Database links: Entrez Gene: 83986 Human SwissProt: Q9H0X4 Human Unigene: 513225 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
整合素是由非共价结合的跨膜α和β亚基组成的异源二聚体。十六个α和八个β亚基异源二聚以产生超过20个不同的受体。某些整合素也可以与可溶性配体如纤维蛋白原结合，或与相邻细胞上的受体（如细胞内粘附分子（ICAMs））结合，从而导致细胞聚集。整合素除了介导细胞粘附和细胞骨架组织外，还起着信号受体的作用。整合素转导的信号在许多生物学过程中起着重要作用，包括细胞生长、分化、迁移和凋亡。ITFG3（整合素α-FG-GAP重复序列包含3），也称为C16ORF9，是一种含有552个氨基酸的单程跨膜蛋白，含有FG-间隙重复序列，这是整合素蛋白中常见的一个基序。作为替代剪接事件的结果，产生了两种异构体ITFG3。