CHIT1 (Human) Recombinant Protein (Q01)
产品名称： CHIT1 (Human) Recombinant Protein (Q01)
英文名称： CHIT1 (Human) Recombinant Protein (Q01)
产品编号： H00001118-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human CHIT1 partial ORF ( NP_003456.1, 60 a.a. - 169 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- GMTNHQLSTTEWNDETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQE
- Theoretical MW (kDa):
- 37.84
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 1118
- GeneBank Accession#:
- NM_003465
- Protein Accession#:
- NP_003456.1
- Gene Name:
- CHIT1
- Gene Alias:
- CHI3,CHIT,FLJ00314,MGC125322
- Gene Description:
- chitinase 1 (chitotriosidase)
- Omim ID:
- 600031
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. [provided by RefSeq
- Other Designations:
- chitotriosidase,plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
- Gene Pathway
- Related Disease
- Acute Disease
- Asthma
- Asthma
- Candidiasis
- Cardiovascular Diseases
- Chronic Disease
- Coronary Artery Disease
- Diabetes Mellitus, Type 2
- Edema
- Elephantiasis, Filarial
- Genetic Predisposition to Disease
- Gram-Negative Bacterial Infections
- Hypersensitivity
- Hypertension
- Leukemia
- Leukemia, Myeloid
- Leukemia, Myeloid, Acute
- Malaria
- Sepsis