FITC标记的BRD2蛋白抗体
产品名称： FITC标记的BRD2蛋白抗体
英文名称： Anti-BRD2/FITC
产品编号： HZ-12888R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-BRD2/FITC Conjugated antibody
FITC标记的BRD2蛋白抗体
| 英文名称 | Anti-BRD2/FITC |
| 中文名称 | FITC标记的BRD2蛋白抗体 |
| 别 名 | BRD 2; Brd2; BRD2_HUMAN; Bromodomain containing 2; BROMODOMAIN CONTAINING PROTEIN2; Bromodomain-containing protein 2; D6S113E; DKFZp686N0336; female sterile homeotic related gene 1; FLJ31942; FSH; FSRG1; KIAA9001; NAT; O27.1.1; Really interesting new gene 3 protein; Ring3; RING3 PROTEIN; RNF3. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 信号转导 激酶和磷酸酶 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 88kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BRD2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The bromodomain-containing proteins include BRD2, BRD3, BRD4 and BRDT. BRD2 (RING3 protein) is a mitogen-activated nuclear protein whose gene is located in the human MHC II region, suggesting its relation to HLA-associated diseases. The gene encoding BRD3 (RING3-like protein) contains two bromodomains and maps to chromosome 9q34. BRD4 (HUNK1 protein) is a nuclear protein involved in the regulation of chromosomal dynamics during mitosis. The testis-specific bromodomain protein BRDT contains a PEST sequence, indicating that it undergoes rapid intracellular degradation. The bromodomain-containing proteins are ubiquitously expressed. Function: May play a role in spermatogenesis or folliculogenesis. Subunit: Homodimer. Interacts with E2F1 and with histone H4acetylated at 'Lys-13'. Subcellular Location: Nucleus. Similarity: Contains 2 bromo domains. Contains 1 ET domain. Database links: Entrez Gene: 6046 Human Entrez Gene: 14312 Mouse Entrez Gene: 294276 Rat Omim: 601540 Human SwissProt: P25440 Human SwissProt: Q7JJ13 Mouse SwissProt: Q6MGA9 Rat Unigene: 75243 Human Unigene: 3444 Mouse Unigene: 98146 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
含溴蛋白的蛋白质包括BRD2、BRD3、BRD4和BRDT。BRD2(RING3蛋白)是一种丝裂原激活的核蛋白，其基因位于人MHCⅡ区，提示其与HLA相关疾病的关系。编码BRD3（Rang3样蛋白）的基因含有两个溴化酶，并映射到染色体9q34。BRD4（Hunk1蛋白）是一种参与有丝分裂过程中染色体动态调控的核蛋白。睾丸特异性溴代马恩蛋白BRDT包含一个PEST序列，表明它经历快速的细胞内降解。含溴的蛋白质普遍表达。