FITC标记的组织蛋白酶H重连抗体
产品名称： FITC标记的组织蛋白酶H重连抗体
英文名称： Anti-Cathepsin H heavy chain/FITC
产品编号： HZ-10676R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Cathepsin H heavy chain/FITC Conjugated antibody
FITC标记的组织蛋白酶H重连抗体
| 英文名称 | Anti-Cathepsin H heavy chain/FITC |
| 中文名称 | FITC标记的组织蛋白酶H重连抗体 |
| 别 名 | CTSH; Cathepsin H; ACC4; ACC5; Cathepsin H heavy chain; CPSB; cath-H; CH; Ctsh; CATH_HUMAN; Pro-cathepsin H. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 转录调节因子 合成与降解 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 19kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Cathepsin H heavy chain |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in various cellular events such as peptide biosynthesis and protein degradation. The propeptide region of cathepsin H is highly homologous to other cathepsins. This region is thought to play a role in the processing of cysteine proteases. Cathepsin H is thought to be involved in several pathological conditions, including neuro degenerative disorders and cancer. Function: Important for the overall degradation of proteins in lysosomes. Subunit: Composed of a mini chain and a large chain. The large chain may be split into heavy and light chain. All chains are held together by disulfide bonds. Subcellular Location: Lysosome. Similarity: Belongs to the peptidase C1 family. Database links: Entrez Gene: 1512 Human Entrez Gene: 25425 Rat Omim: 116820 Human SwissProt: P09668 Human SwissProt: P00786 Rat Unigene: 148641 Human Unigene: 1997 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
cathepsin家族的蛋白水解酶含有几种不同种类的蛋白酶。半胱氨酸蛋白酶类包括组织蛋白酶B、L、H、K、S和O。天冬氨酸蛋白酶类由组织蛋白酶D和E组成。大多数组织蛋白酶是溶酶体，每个都参与各种细胞事件，如肽生物合成和蛋白质降解。组织蛋白酶H的前肽区与其他组织蛋白酶高度同源。该区域被认为在半胱氨酸蛋白酶的加工中起作用。组织蛋白酶H被认为参与多种病理条件，包括神经退行性疾病和癌症。