Product Information
    
 
    

    

        

            

                

                
Product Name
                
                

                
Cat#
                
                

                
Size
                
                

                
Price（¥）
                
            
            

                

                
Recombinant Mouse Macrophage Colony-stimulating Factor (Mouse M-CSF)
                
                

                
91109ES10
                
                

                
10 μg
                
                

                
1855.00
                
            
            

                

                
91109ES60
                
                

                
100 μg
                
                

                
11255.00
                
            
            

                

                
91109ES76
                
                

                
500 μg
                
                

                
29275.00
                
            
        
    
    
    
 
    
Product Description
    
 
    
Monocyte colony-stimulating factor (M-CSF, CSF-1) is a macrophage lineage-specific growth factor. Full length human M-CSF transcripts encode a 522 amino acid (aa) type I transmembrane (TM) protein with a 464 aa extracellular region, a 21 aa TM domain, and a 37 aa cytoplasmic tail that forms a 140 kDa covalent dimer. The first 223 aa of mature human M-CSF shares 88%, 86%, 81% and 74% aa identity with corresponding regions of dog, cow, mouse and rat MCSF, respectively. M-CSF Induces vascular endothelial growth factor production and angiogenic activity from human monocytes. Whatmore, M-CSF and GM-CSF are mediators involved in regulating the numbers and function of macrophage lineage populations and have been shown to contribute to macrophage heterogeneity. 
    
 
    
Product Properties
    
 
    

    

        

            

                

                
Synonyms
                
                

                
CSF-1, MGI-IM, MCSF, M-CSF, MGC31930
                
            
            

                

                
Accession
                
                

                
Q3U4F9
                
            
            

                

                
UniGene
                
                

                
Mm.795.
                
            
            

                

                
Source
                
                

                
E.coli-derived Mouse M-CSF protein, Lys33-Glu262.
                
            
            

                

                
Molecular Weight
                
                

                
Approximately 52.0 kDa.
                
            
            

                

                
AA Sequence
                
                

                
KEVSEHCSHM IGNGHLKVLQ QLIDSQMETS CQIAFEFVDQ EQLDDPVCYL KKAFFLVQDI IDETMRFKDN TPNANATERL QELSNNLNSC FTKDYEEQNK ACVRTFHETP LQLLEKIKNF FNETKNLLEK DWNIFTKNCN NSFAKCSSRD VVTKPDCNCL YPKATPSSDP ASASPHQPPA PSMAPLAGLA WDDSQRTEGS SLLPSELPLR IEDPGSAKQR PPRSTCQTLE
                
            
            

                

                
Tag
                
                

                
None
                
            
            

                

                
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