产品概述：Purified recombinant protein of Human synaptosomal-associated protein, 23kDa (SNAP23), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

蛋白长度：A DNA sequence encoding full-length of SNAP23

表达系统：E. coli

种属：Human

标签类型：N-GST and C-His

分子量：45.6 kDa

通用名：SNAP23

总结：Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

别名：HsT17016; SNAP-23; SNAP23A; SNAP23B