FITC标记的人类疱疹病毒8抗体
产品名称： FITC标记的人类疱疹病毒8抗体
英文名称： Anti-HHV8 ORF8/FITC
产品编号： HZ-16860R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-HHV8 ORF8/FITC Conjugated antibody
FITC标记的人类疱疹病毒8抗体
| 英文名称 | Anti-HHV8 ORF8/FITC |
| 中文名称 | FITC标记的人类疱疹病毒8抗体 |
| 别 名 | Human herpes virus 8 Glycoprotein B-like; HHV 8; Human herpes virus 8; Human herpesvirus 8; Kaposi's sarcoma herpes virus; Kaposi's sarcoma herpes virus; KSHV; ORF8; GB_HHV8P. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细菌及病毒 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | HHV8 |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 92kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from HHV8/ORF8 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein. Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells. Function: Envelope glycoprotein that forms spikes at the surface of the virion envelope. Participates in viral entry through an RGD motif that binds ITGAV-ITGB3. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. Subunit: Homotrimer; disulfide-linked (By similarity) Subcellular Location: Virion membrane Similarity: Belongs to the herpesviridae glycoprotein B family Database links: Entrez Gene: 4961501 HHV8 ORF8 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
kaposi'腺肉瘤疱疹病毒（KSHV）belongs to theγ-疱疹病毒（2）subfamily and has been to the kaposi' closely联原发性肉瘤，淋巴瘤和多发性effusion（PEL）castleman'阿尔茨海默病。KSHV基因组is of the 165～170 KB和contains least 88开放阅读框架。KSHV orf8 is a病毒信封相关蛋白。阿库拉等人（2003年）：报告的行为介导的信号转导在as a病毒糖蛋白B的输入。糖蛋白possesses this the Arg-Gly-Asp（RGD）基序和α3、β1整合素utilizes as one of the entry into the for its受体的靶细胞。