FITC标记的密度调节蛋白抗体
产品名称： FITC标记的密度调节蛋白抗体
英文名称： Anti-Density Regulated Protein/FITC
产品编号： HZ-14276R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Density Regulated Protein/FITC Conjugated antibody
FITC标记的密度调节蛋白抗体
| 英文名称 | Anti-Density Regulated Protein/FITC |
| 中文名称 | FITC标记的密度调节蛋白抗体 |
| 别 名 | denr; DENR_HUMAN; Density regulated protein; Density-regulated protein; DRP; DRP1; DRP1 protein; Protein DRP1; SMAP-3; SMAP3; Smooth muscle cell associated protein 3; Smooth muscle cell-associated protein 3. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 转运蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 22kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Density Regulated Protein |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants. [provided by RefSeq, Jul 2008] Function: May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1. Tissue Specificity: Highly expressed in heart and skeletal muscle and moderately expressed in the brain, placenta, liver and pancreas. Weakly expressed in the lung and kidney. Similarity: Belongs to the DENR family. Contains 1 SUI1 domain. Database links: Entrez Gene: 8562 Human Entrez Gene: 771794 Chicken Entrez Gene: 614238 Cow Entrez Gene: 68184 Mouse Entrez Gene: 360806 Rat Entrez Gene: 444615 Xenopus laevis Omim: 604550 Human SwissProt: Q5ZJ39 Chicken SwissProt: Q2HJ47 Cow SwissProt: O43583 Human SwissProt: Q9CQJ6 Mouse SwissProt: Q6GLZ1 Xenopus laevis SwissProt: Q6DFN7 Xenopus tropicalis Unigene: 22393 Human Unigene: 28549 Mouse Unigene: 7540 Xenopus laevis Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
该基因编码一种蛋白质，其在高密度培养细胞中的表达增加，但在生长停滞期间不表达。该基因还显示在HER-2/NEU原癌基因过表达的细胞中有增加的表达。蛋白质含有一个SUI1结构域。在芽殖酵母中，SUI1是翻译起始因子，它与eIF-2和启动子tRNA-Met一起将核糖体引导到合适的翻译起始位点。在哺乳动物、昆虫和PL中发现了类似于SUI的蛋白质。